Part Number
Part Number:
NSN:
NIIN:
Item Name:
GLUTATHIONE PEROXID
CAGE Information
| Code | Company |
|---|---|
| 4SM76 | NORTHWEST LIFE SCIENCE SPECIALTIES L |
Characteristics (Decoded)
| MRC | Requirements Statement | Clear Text Reply |
|---|---|---|
| FEAT | SPECIAL FEATURES | GLUTATHIONE PEROXIDASE (GPX) (EC 1.11.1.9) ENZYMES BELONG TO A FAMILY OF SELENOPROTEINS WHOSE FUNCTION IS TO CATALYZE THE REDUCTION OF VARIOUS PEROXIDES. FOUR TYPES OF GPX (GPX-1 TO 4) HAVE BEEN IDENTIFIED IN MAMMALIAN SPECIES. GPX-1 IS THE CLASSIC INTRACELLULAR FORM WHILE GPX-2, GPX-3 AND GPX-4 ARE GASTROINTESTINAL, PLASMA AND PHOSPHOLIPID HYDROPEROXIDASE FORMS; RESPECTIVELY. THREE OF THE FORMS ARE TETRAMERS COMPOSED OF 4 IDENTICAL 22 KDA MONOMERS WHILE GPX-4 IS MONOMERIC. THE MONOMERIC SUBUNITS OF GPX-1 TO 3 EACH HAVE THE AMINO ACID SELENOCYSTEIN AT THE ACTIVE SITE OF THE ENZYME. THE BEST CHARACTERIZED AND MOST HEAVILY RESEARCHED FORM IS GPX-1, THE INTRACELLULAR FORM, SOMETIMES ALSO CALLED CELLULAR GPX (CGPX). |